Epidemiology of B27-associated diseases.

Epidemiology of B27-associated diseases.

Genetics of B27-associated diseases--2.

Genetics of B27-associated diseases--1.

The genetic analysis of those conditions that show familial aggregation, in the absence of recognisable patterns of Mendelian segregation, has proved to be very difficult. A generalised model would allow for the possibility of more than one disease susceptibility gene and for the influence of environmental factors. The pedigree illustrated in Fig. 1 includes patients with Reiter's syndrome (RS)...

Identification of HLA-B27-restricted peptides from the Chlamydia trachomatis proteome with possible relevance to HLA-B27-associated diseases.

The association of HLA-B27 with ankylosing spondylitis and reactive arthritis is the strongest one known between an MHC class I Ag and a disease. We have searched the proteome of the bacterium Chlamydia trachomatis for HLA-B27 binding peptides that are stimulatory for CD8(+) cells both in a model of HLA-B27 transgenic mice and in patients. This was done by combining two biomathematical computer...

orofacial manifestations of neurological diseases

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